Anti-GITR therapy promotes immunity against malignant glioma in a murine model

Regulatory T cells (Tregs) are potently immunosuppressive cells that accumulate within the glioma microenvironment. The reduction in their function and/or trafficking has been previously shown to enhance survival in preclinical models of glioma. Glucocorticoid-induced TNFR-related protein (GITR) is...

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Dades bibliogràfiques
Publicat a:Cancer Immunol Immunother
Autors principals: Miska, Jason, Rashidi, Aida, Chang, Alan L., Muroski, Megan E., Han, Yu, Zhang, Lingjiao, Lesniak, Maciej S.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101166/
https://ncbi.nlm.nih.gov/pubmed/27734112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1912-8
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