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EXTH-67. TG02, A BRAIN-PENETRANT MULTI-CDK INHIBITOR, POTENTLY SUPPRESSES MYC-DRIVEN GLIOBLASTOMA
MYC is a central driver of tumorigenesis in many malignancies, including the universally lethal glioblastoma (GBM). However, developing direct inhibitors of MYC have proven challenging. One appealing alternative strategy to target MYC-driven cancers is to interfere with the signaling program necessa...
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| Publicat a: | Neuro Oncol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692149/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.359 |
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