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EXTH-02. DUAL DRUG MODIFIED NANOVESICLES FOR ENHANCING THE THERAPEUTIC EFFICACY OF DOXORUBICIN TOWARDS GLIOBLASTOMA AND MPNST

Doxorubicin is a topoisomerase II inhibitor demonstrated to be effective in several cancers including malignant peripheral nerve sheath tumors (MPNST) and glioblastoma in cell culture, but at higher dose causes adverse effects like cardiotoxicity in patients. This minimizes the therapeutic dosage of...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Madhankumar, A B, Mrowczynski, Oliver, Maurer, Robert, Slagle-Webb, Becky, Rizk, Elias, Zacharia, Brad, Connor, James
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216916/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.351
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