TMIC-04. A POTENT MICROGLIAL RESPONSE TO BLOCKING THE CD47-SIRPα ANTI-PHAGOCYTIC AXIS OVERCOMES DEFICIENT MACROPHAGE RECRUITMENT DURING ANTI-CD47 IMMUNOTHERAPY AGAINST GLIOBLASTOMA

Modulation of tumor-associated macrophages and microglia (TAMs) in glioblastoma (GBM) is a promising anti-tumor strategy. However, little is known about the phenotypic organization of the TAM-pool and the role of GBM subtypes in shaping their specific immunologic environment. Therefore, we sought to...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Hutter, Gregor, Theruvath, Johanna, Graef, Claus Moritz, Weissman, Irving, Mitra, Siddhartha S, Cheshier, Samuel H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692095/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.994
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