CSIG-20. INHIBITION OF AKT/SURVIVIN AND AKT/ID3 PATHWAYS BY CELECOXIB, A SELECTIVE COX-2 INHIBITOR, MAY HAVE PROMISING THERAPEUTIC POTENTIAL IN LOW-GRADE GLIOMA

Approximately half of the patients with low-grade glioma (LGG) treated surgically suffer recurrence or metastasis. Malignant transformation sometimes occurs after several years and no effective drug treatment has been established yet. Though the selective COX-2 inhibitor celecoxib showed anti-tumor...

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Publicado en:Neuro Oncol
Main Authors: Yamaguchi, Izumi, Sato, Aya, Mizobuchi, Yoshifumi, Nakajima, Kohei, Fujihara, Toshitaka, Shono, Kenji, Kitazato, Keiko, Sumi, Akiko, Nagahiro, Shinji
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Abstracts
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691934/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.214
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