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SCDT-04. POLYION COMPLEX-MEDIATED INTRAVENOUS DELIVERY OF ANTISENSE OLIGONUCLEOTIDES AGAINST THE NOTCH-REGULATED NON-CODING RNA TUG1 IN GLIOMA
Long ncRNAs (lncRNAs) have been increasingly demonstrated to affect the tumor progression via altering chromatin structure and miRNA-mediated gene regulation. We found that Notch1 activation in glioma-stem cells (GSC) specifically induces expression of the lncRNA, TUG1. TUG1 coordinately promotes se...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5691894/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1087 |
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