Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment

Targeting self-renewal is an important goal in cancer therapy and recent studies have focused on Notch signalling in the maintenance of stemness of glioma stem cells (GSCs). Understanding cancer-specific Notch regulation would improve specificity of targeting this pathway. In this study, we find tha...

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Udgivet i:Nat Commun
Main Authors: Katsushima, Keisuke, Natsume, Atsushi, Ohka, Fumiharu, Shinjo, Keiko, Hatanaka, Akira, Ichimura, Norihisa, Sato, Shinya, Takahashi, Satoru, Kimura, Hiroshi, Totoki, Yasushi, Shibata, Tatsuhiro, Naito, Mitsuru, Kim, Hyun Jin, Miyata, Kanjiro, Kataoka, Kazunori, Kondo, Yutaka
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150648/
https://ncbi.nlm.nih.gov/pubmed/27922002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13616
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