Contribution of MicroRNA-1275 to Claudin11 Protein Suppression via a Polycomb-mediated Silencing Mechanism in Human Glioma Stem-like Cells

Glioblastomas show heterogeneous histological features, and tumor cells show distinct phenotypic states that confer different functional attributes and an aggressive character. However, the molecular mechanisms underlying the heterogeneity in this disease are poorly understood. Glioma stem-like cell...

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Autores principales: Katsushima, Keisuke, Shinjo, Keiko, Natsume, Atsushi, Ohka, Fumiharu, Fujii, Makiko, Osada, Hirotaka, Sekido, Yoshitaka, Kondo, Yutaka
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Molecular Bases of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431641/
https://ncbi.nlm.nih.gov/pubmed/22736761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359109
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