Polyprotein Processing as a Determinant for In Vitro Activity of Semliki Forest Virus Replicase

Semliki Forest virus (SFV) is an arthropod-borne alphavirus that induces membrane invaginations (spherules) in host cells. These harbor the viral replication complexes (RC) that synthesize viral RNA. Alphaviruses have four replicase or nonstructural proteins (nsPs), nsP1–4, expressed as polyprotein...

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Enregistré dans:
Détails bibliographiques
Publié dans:Viruses
Auteurs principaux: Pietilä, Maija K., Albulescu, Irina C., van Hemert, Martijn J., Ahola, Tero
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691643/
https://ncbi.nlm.nih.gov/pubmed/28991178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9100292
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