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Polyprotein Processing as a Determinant for In Vitro Activity of Semliki Forest Virus Replicase

Semliki Forest virus (SFV) is an arthropod-borne alphavirus that induces membrane invaginations (spherules) in host cells. These harbor the viral replication complexes (RC) that synthesize viral RNA. Alphaviruses have four replicase or nonstructural proteins (nsPs), nsP1–4, expressed as polyprotein...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Pietilä, Maija K., Albulescu, Irina C., van Hemert, Martijn J., Ahola, Tero
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691643/
https://ncbi.nlm.nih.gov/pubmed/28991178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9100292
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