Polyprotein Processing as a Determinant for In Vitro Activity of Semliki Forest Virus Replicase

Semliki Forest virus (SFV) is an arthropod-borne alphavirus that induces membrane invaginations (spherules) in host cells. These harbor the viral replication complexes (RC) that synthesize viral RNA. Alphaviruses have four replicase or nonstructural proteins (nsPs), nsP1–4, expressed as polyprotein...

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Publicado en:Viruses
Autores principales: Pietilä, Maija K., Albulescu, Irina C., van Hemert, Martijn J., Ahola, Tero
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691643/
https://ncbi.nlm.nih.gov/pubmed/28991178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9100292
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