The Mincle ligand trehalose dibehenate differentially modulates M1‐like and M2‐like macrophage phenotype and function via Syk signaling

INTRODUCTION: Macrophages play a significant role in the progression of diseases, such as cancer, making them a target for immune‐modulating agents. Trehalose dibehenate (TDB) is known to activate M1‐like macrophages via Mincle, however, the effect of TDB on M2‐like macrophages, which are found in t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Kodar, Kristel, Harper, Jacquie L., McConnell, Melanie J., Timmer, Mattie S. M., Stocker, Bridget L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691301/
https://ncbi.nlm.nih.gov/pubmed/28722316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.186
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados