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6,6′-Aryl Trehalose Analogs as Potential Mincle Ligands
6,6′-Aryl trehalose derivatives have been synthesized with a view towards identifying novel Th-17-inducing vaccine adjuvants based on the high affinity Mincle ligand Brartemicin.The initial structure-activity relationships of these novel trehalose-based compounds were investigated. All compounds hav...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7372699/ https://ncbi.nlm.nih.gov/pubmed/32616186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115564 |
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