Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

Dysregulation of autophagy and inflammasome activity contributes to the development of auto-inflammatory diseases. Emerging evidence highlights the importance of the actin cytoskeleton in modulating inflammatory responses. Here we show that deficiency of Wiskott–Aldrich syndrome protein (WASp), whic...

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Publicado no:Nat Commun
Main Authors: Lee, Pamela P., Lobato-Márquez, Damián, Pramanik, Nayani, Sirianni, Andrea, Daza-Cajigal, Vanessa, Rivers, Elizabeth, Cavazza, Alessia, Bouma, Gerben, Moulding, Dale, Hultenby, Kjell, Westerberg, Lisa S., Hollinshead, Michael, Lau, Yu-Lung, Burns, Siobhan O., Mostowy, Serge, Bajaj-Elliott, Mona, Thrasher, Adrian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691069/
https://ncbi.nlm.nih.gov/pubmed/29146903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01676-0
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