PD-1 status in CD8(+) T cells associates with survival and anti-PD-1 therapeutic outcomes in head and neck cancer

Improved understanding of expression of immune checkpoint receptors (ICR) on tumor-infiltrating lymphocytes (TIL) may facilitate more effective immunotherapy in head and neck cancer (HNC) patients. A higher frequency of PD-1(+) TIL has been reported in human papillomavirus (HPV)(+) HNC patients, des...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Kansy, Benjamin A., Concha-Benavente, Fernando, Srivastava, Raghvendra M., Jie, Hyun-Bae, Shayan, Gulidanna, Lei, Yu, Moskovitz, Jessica, Moy, Jennifer, Li, Jing, Brandau, Sven, Lang, Stephan, Schmitt, Nicole C., Freeman, Gordon J., Gooding, William E., Clump, David A., Ferris, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690836/
https://ncbi.nlm.nih.gov/pubmed/28904066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-3167
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