STING activation enhances cetuximab-mediated NK cell activation and DC maturation and correlates with HPV(+) status in head and neck cancer

OBJECTIVES: The intracellular DNA sensor stimulator of interferon genes (STING) has recently been shown to play a vital role in anti-viral and anti-tumor immune responses stimulating cytokine production. While human papillomavirus (HPV) is a causative agent for a subset of head and neck squamous cel...

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Vydáno v:Oral Oncol
Hlavní autoři: Lu, Shanhong, Concha-Benavente, Fernando, Shayan, Gulidanna, Srivastava, Raghvendra M., Gibson, Sandra P., Wang, Lin, Gooding, William E., Ferris, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877820/
https://ncbi.nlm.nih.gov/pubmed/29496049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2018.01.019
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