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STING activation enhances cetuximab-mediated NK cell activation and DC maturation and correlates with HPV(+) status in head and neck cancer

OBJECTIVES: The intracellular DNA sensor stimulator of interferon genes (STING) has recently been shown to play a vital role in anti-viral and anti-tumor immune responses stimulating cytokine production. While human papillomavirus (HPV) is a causative agent for a subset of head and neck squamous cel...

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Detalhes bibliográficos
Publicado no:Oral Oncol
Main Authors: Lu, Shanhong, Concha-Benavente, Fernando, Shayan, Gulidanna, Srivastava, Raghvendra M., Gibson, Sandra P., Wang, Lin, Gooding, William E., Ferris, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877820/
https://ncbi.nlm.nih.gov/pubmed/29496049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2018.01.019
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