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PD-L1 Mediates Dysfunction in Activated PD-1(+) NK Cells in Head and Neck Cancer Patients

Inhibitory immune-checkpoint receptors (ICRs), including programmed death 1 (PD-1), have been characterized as exhaustion markers on T cells that infiltrate the tumor micro-environment (TME) of many cancer types, including head and neck cancer (HNC). However, expression and function of ICRs, includi...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Concha-Benavente, Fernando, Kansy, Benjamin, Moskovitz, Jessica, Moy, Jennifer, Chandran, Uma, Ferris, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512340/
https://ncbi.nlm.nih.gov/pubmed/30282672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0062
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