ロード中...
The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin
BACKGROUND: Fibrosing diseases are a leading cause of morbidity and mortality worldwide and, therefore, there is a need for safe and effective antifibrotic therapies. Adenosine, generated extracellularly by the dephosphorylation of adenine nucleotides, ligates specific receptors which play a critica...
保存先:
| 出版年: | PLoS One |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5690602/ https://ncbi.nlm.nih.gov/pubmed/29145453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188135 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|