Sepsis reveals compartment-specific responses in intestinal proliferation and apoptosis in transgenic mice whose enterocytes re-enter the cell cycle

Cell production and death are tightly regulated in the rapidly renewing gut epithelium, with proliferation confined to crypts and apoptosis occurring in villi and crypts. This study sought to determine how stress alters these compartmentalized processes. Wild-type mice made septic via cecal ligation...

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Detalles Bibliográficos
Publicado en:FASEB J
Autores principales: Lyons, John D., Klingensmith, Nathan J., Otani, Shunsuke, Mittal, Rohit, Liang, Zhe, Ford, Mandy L., Coopersmith, Craig M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690387/
https://ncbi.nlm.nih.gov/pubmed/28842422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700015RR
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