Sepsis reveals compartment-specific responses in intestinal proliferation and apoptosis in transgenic mice whose enterocytes re-enter the cell cycle

Cell production and death are tightly regulated in the rapidly renewing gut epithelium, with proliferation confined to crypts and apoptosis occurring in villi and crypts. This study sought to determine how stress alters these compartmentalized processes. Wild-type mice made septic via cecal ligation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB J
Prif Awduron: Lyons, John D., Klingensmith, Nathan J., Otani, Shunsuke, Mittal, Rohit, Liang, Zhe, Ford, Mandy L., Coopersmith, Craig M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Federation of American Societies for Experimental Biology 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690387/
https://ncbi.nlm.nih.gov/pubmed/28842422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700015RR
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