Sepsis reveals compartment-specific responses in intestinal proliferation and apoptosis in transgenic mice whose enterocytes re-enter the cell cycle

Cell production and death are tightly regulated in the rapidly renewing gut epithelium, with proliferation confined to crypts and apoptosis occurring in villi and crypts. This study sought to determine how stress alters these compartmentalized processes. Wild-type mice made septic via cecal ligation...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Lyons, John D., Klingensmith, Nathan J., Otani, Shunsuke, Mittal, Rohit, Liang, Zhe, Ford, Mandy L., Coopersmith, Craig M.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690387/
https://ncbi.nlm.nih.gov/pubmed/28842422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700015RR
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