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Chronic alcohol ingestion worsens survival and alters gut epithelial apoptosis and CD8(+) T cell function after Pseudomonas aeruginosa pneumonia-induced sepsis

Mortality is higher in septic patients with a history of alcohol use disorder than in septic patients without a history of chronic alcohol usage. We have previously described a model of chronic alcohol ingestion followed by sepsis from cecal ligation and puncture in which alcohol-fed septic mice hav...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Klingensmith, Nathan J., Fay, Katherine T., Lyons, John D., Chen, Ching-wen, Otani, Shunsuke, Liang, Zhe, Chihade, Deena B., Burd, Eileen M., Ford, Mandy L., Coopersmith, Craig M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191382/
https://ncbi.nlm.nih.gov/pubmed/29664837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001163
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