Novel post-transcriptional and post-translational regulation of pro-apoptotic protein BOK and anti-apoptotic protein Mcl-1 determine the fate of breast cancer cells to survive or die

Deregulation of apoptosis is central to cancer progression and a major obstacle to effective treatment. The Bcl-2 gene family members play important roles in the regulation of apoptosis and are frequently altered in cancers. One such member is pro-apoptotic protein Bcl-2-related Ovarian Killer (BOK)...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Onyeagucha, Benjamin, Subbarayalu, Panneerdoss, Abdelfattah, Nourhan, Rajamanickam, Subapriya, Timilsina, Santosh, Guzman, Rosa, Zeballos, Carla, Eedunuri, Vijay, Bansal, Sanjay, Mohammad, Tabrez, Chen, Yidong, Vadlamudi, Ratna K., Rao, Manjeet K.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689661/
https://ncbi.nlm.nih.gov/pubmed/29156771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20841
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