Cross-talk among writers, readers, and erasers of m(6)A regulates cancer growth and progression

The importance of RNA methylation in biological processes is an emerging focus of investigation. We report that altering m(6)A levels by silencing either N(6)-adenosine methyltransferase METTL14 (methyltransferase-like 14) or demethylase ALKBH5 (ALKB homolog 5) inhibits cancer growth and invasion. M...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Panneerdoss, Subbarayalu, Eedunuri, Vijay K., Yadav, Pooja, Timilsina, Santosh, Rajamanickam, Subapriya, Viswanadhapalli, Suryavathi, Abdelfattah, Nourhan, Onyeagucha, Benjamin C., Cui, Xiadong, Lai, Zhao, Mohammad, Tabrez A., Gupta, Yogesh K., Huang, Tim Hui-Ming, Huang, Yufei, Chen, Yidong, Rao, Manjeet K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170038/
https://ncbi.nlm.nih.gov/pubmed/30306128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aar8263
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