Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis

PURPOSE: The approaches aimed at inhibiting the ability of cancer cells to repair DNA strand breaks have emerged as promising targets for treating cancers. Here, we assessed the potential of imipramine blue (IB), a novel analogue of anti-depressant imipramine, to suppress breast cancer growth and me...

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Publicado no:Clin Cancer Res
Main Authors: Rajamanickam, Subapriya, Panneerdoss, Subbarayalu, Gorthi, Aparna, Timilsina, Santosh, Onyeagucha, Benjamin, Kovalsky, Dmytro, Ivanov, Dmitri, Hanes, Martha A., Vadlamudi, Ratna, Chen, Yidong, Bishop, Alexander J, Arbiser, Jack L, Rao, Manjeet K
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947433/
https://ncbi.nlm.nih.gov/pubmed/26927663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2535
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