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Enhancement of BLM-DNA2-mediated long-range DNA end resection by CtIP

DNA double-strand break repair by homologous recombination entails the resection of DNA ends to reveal ssDNA tails, which are used to invade a homologous DNA template. CtIP and its yeast ortholog Sae2 regulate the nuclease activity of MRE11 in the initial stage of resection. Deletion of CtIP in the...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Daley, James M., Jimenez-Sainz, Judit, Wang, Weibin, Miller, Adam S., Xue, Xiaoyu, Nguyen, Kevin A., Jensen, Ryan B., Sung, Patrick
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689478/
https://ncbi.nlm.nih.gov/pubmed/29020620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.048
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