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Enhancement of BLM-DNA2-mediated long-range DNA end resection by CtIP
DNA double-strand break repair by homologous recombination entails the resection of DNA ends to reveal ssDNA tails, which are used to invade a homologous DNA template. CtIP and its yeast ortholog Sae2 regulate the nuclease activity of MRE11 in the initial stage of resection. Deletion of CtIP in the...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5689478/ https://ncbi.nlm.nih.gov/pubmed/29020620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.048 |
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