Changes in LXR signaling influence early-pregnancy lipogenesis and protect against dysregulated fetoplacental lipid homeostasis

Human pregnancy is associated with enhanced de novo lipogenesis in the early stages followed by hyperlipidemia during advanced gestation. Liver X receptors (LXRs) are oxysterol-activated nuclear receptors that stimulate de novo lipogenesis and also promote the efflux of cholesterol from extrahepatic...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Endocrinol Metab
Hoofdauteurs: Nikolova, Vanya, Papacleovoulou, Georgia, Bellafante, Elena, Borges Manna, Luiza, Jansen, Eugene, Baron, Silvère, Abu-Hayyeh, Shadi, Parker, Malcolm, Williamson, Catherine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689017/
https://ncbi.nlm.nih.gov/pubmed/28420650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00449.2016
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