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Conservation of tRNA mimicry in the 5′-untranslated region of distinct HIV-1 subtypes

Human tRNA(Lys3) serves as the primer for reverse transcription in human immunodeficiency virus type-1 (HIV-1) and anneals to the complementary primer binding site (PBS) in the genome. All tRNA(Lys) isoacceptors interact with human lysyl-tRNA synthetase (hLysRS) and are selectively packaged into vir...

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Pubblicato in:RNA
Autori principali: Comandur, Roopa, Olson, Erik D., Musier-Forsyth, Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689005/
https://ncbi.nlm.nih.gov/pubmed/28860303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.062182.117
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