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Total RNA-seq to identify pharmacological effects on specific stages of mRNA synthesis
Pharmacological perturbation is a powerful tool for understanding mRNA synthesis, but identification of the specific steps of this multi-step process that are targeted by small molecules remains challenging. Here we applied strand-specific total RNA sequencing (RNA-seq) to identify and distinguish s...
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| Udgivet i: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5688950/ https://ncbi.nlm.nih.gov/pubmed/28263964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2317 |
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