SnapShot-Seq: A Method for Extracting Genome-Wide, In Vivo mRNA Dynamics from a Single Total RNA Sample

mRNA synthesis, processing, and destruction involve a complex series of molecular steps that are incompletely understood. Because the RNA intermediates in each of these steps have finite lifetimes, extensive mechanistic and dynamical information is encoded in total cellular RNA. Here we report the d...

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Autors principals: Gray, Jesse M., Harmin, David A., Boswell, Sarah A., Cloonan, Nicole, Mullen, Thomas E., Ling, Joseph J., Miller, Nimrod, Kuersten, Scott, Ma, Yong-Chao, McCarroll, Steven A., Grimmond, Sean M., Springer, Michael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935918/
https://ncbi.nlm.nih.gov/pubmed/24586954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089673
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