Sodium channel Na(V)1.3 is important for enterochromaffin cell excitability and serotonin release

In the gastrointestinal (GI) epithelium, enterochromaffin (EC) cells are enteroendocrine cells responsible for producing >90% of the body’s serotonin (5-hydroxytryptamine, 5-HT). However, the molecular mechanisms of EC cell function are poorly understood. Here, we found that EC cells in mouse pri...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Strege, Peter R., Knutson, Kaitlyn, Eggers, Samuel J., Li, Joyce H., Wang, Fan, Linden, David, Szurszewski, Joseph H., Milescu, Lorin, Leiter, Andrew B., Farrugia, Gianrico, Beyder, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688111/
https://ncbi.nlm.nih.gov/pubmed/29142310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15834-3
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