Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

Gut microbiota alterations have been described in several diseases with altered gastrointestinal (GI) motility, and awareness is increasing regarding the role of the gut microbiome in modulating GI function. Serotonin [5-hydroxytryptamine (5-HT)] is a key regulator of GI motility and secretion. To d...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Reigstad, Christopher S., Salmonson, Charles E., Rainey, John F., Szurszewski, Joseph H., Linden, David R., Sonnenburg, Justin L., Farrugia, Gianrico, Kashyap, Purna C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2015
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396604/
https://ncbi.nlm.nih.gov/pubmed/25550456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-259598
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