Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

Gut microbiota alterations have been described in several diseases with altered gastrointestinal (GI) motility, and awareness is increasing regarding the role of the gut microbiome in modulating GI function. Serotonin [5-hydroxytryptamine (5-HT)] is a key regulator of GI motility and secretion. To d...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Reigstad, Christopher S., Salmonson, Charles E., Rainey, John F., Szurszewski, Joseph H., Linden, David R., Sonnenburg, Justin L., Farrugia, Gianrico, Kashyap, Purna C.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396604/
https://ncbi.nlm.nih.gov/pubmed/25550456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-259598
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