Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces

KEY POINTS: The gastrointestinal epithelial enterochromaffin (EC) cell synthesizes the vast majority of the body's serotonin. As a specialized mechanosensor, the EC cell releases this serotonin in response to mechanical forces. However, the molecular mechanism of EC cell mechanotransduction is...

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Bibliografski detalji
Izdano u:J Physiol
Glavni autori: Wang, Fan, Knutson, Kaitlyn, Alcaino, Constanza, Linden, David R., Gibbons, Simon J., Kashyap, Purna, Grover, Madhusudan, Oeckler, Richard, Gottlieb, Philip A., Li, Hui Joyce, Leiter, Andrew B., Farrugia, Gianrico, Beyder, Arthur
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Molecular and cellular
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199733/
https://ncbi.nlm.nih.gov/pubmed/27392819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272718
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