A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family

The NUDIX enzymes are involved in cellular metabolism and homeostasis, as well as mRNA processing. Although highly conserved throughout all organisms, their biological roles and biochemical redundancies remain largely unclear. To address this, we globally resolve their individual properties and inte...

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Publicado no:Nat Commun
Main Authors: Carreras-Puigvert, Jordi, Zitnik, Marinka, Jemth, Ann-Sofie, Carter, Megan, Unterlass, Judith E., Hallström, Björn, Loseva, Olga, Karem, Zhir, Calderón-Montaño, José Manuel, Lindskog, Cecilia, Edqvist, Per-Henrik, Matuszewski, Damian J., Ait Blal, Hammou, Berntsson, Ronnie P. A., Häggblad, Maria, Martens, Ulf, Studham, Matthew, Lundgren, Bo, Wählby, Carolina, Sonnhammer, Erik L. L., Lundberg, Emma, Stenmark, Pål, Zupan, Blaz, Helleday, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688067/
https://ncbi.nlm.nih.gov/pubmed/29142246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01642-w
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