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Gene network inference by probabilistic scoring of relationships from a factorized model of interactions

Motivation: Epistasis analysis is an essential tool of classical genetics for inferring the order of function of genes in a common pathway. Typically, it considers single and double mutant phenotypes and for a pair of genes observes whether a change in the first gene masks the effects of the mutatio...

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Publicado en:Bioinformatics
Main Authors: Žitnik, Marinka, Zupan, Blaž
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229904/
https://ncbi.nlm.nih.gov/pubmed/24931990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu287
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