GSK-3β phosphorylation-dependent degradation of ZNF281 by β-TrCP2 suppresses colorectal cancer progression

Zinc finger protein 281 (ZNF281) has been recently shown to be critical for CRC progression. However, the immediate upstream regulators of ZNF281 remain unclear. Here we reported that the E3 ligase the β-transducin repeat-containing protein 2 (β-TrCP2) governs the ubiquitination and degradation of Z...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhu, Yuekun, Zhou, Qingxin, Zhu, Guiling, Xing, Yanwei, Li, Shiqiang, Ren, Niansheng, Liu, Tianyou, Zhu, Anlong, Bai, Yuxian, Piao, Daxun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687630/
https://ncbi.nlm.nih.gov/pubmed/29179460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20100
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