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Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes

Centrosome separation along the surface of the nucleus at the onset of mitosis is critical for bipolar spindle assembly. Dynein anchored on the nuclear envelope is known to be important for centrosome separation, but it is unclear how nuclear dynein forces are organized in an anisotropic manner to p...

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Foilsithe in:Mol Biol Cell
Main Authors: De Simone, Alessandro, Gönczy, Pierre
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687019/
https://ncbi.nlm.nih.gov/pubmed/28701341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0823
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