Cytoplasmic Dynein Is Required for Distinct Aspects of Mtoc Positioning, Including Centrosome Separation, in the One Cell Stage Caenorhabditis elegans Embryo

We have investigated the role of cytoplasmic dynein in microtubule organizing center (MTOC) positioning using RNA-mediated interference (RNAi) in Caenorhabditis elegans to deplete the product of the dynein heavy chain gene dhc-1. Analysis with time-lapse differential interference contrast microscopy...

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Hauptverfasser: Gönczy, Pierre, Pichler, Silke, Kirkham, Matthew, Hyman, Anthony A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1999
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2164971/
https://ncbi.nlm.nih.gov/pubmed/10508861
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