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EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis
The epidermal growth factor receptor (EGFR), expressed in adrenocorticotrophic hormone (ACTH)–secreting pituitary adenomas causing Cushing disease, regulates ACTH production and corticotroph proliferation. To elucidate the utility of EGFR as a therapeutic target for Cushing disease, we generated tra...
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| Publicado no: | J Endocr Soc |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5686559/ https://ncbi.nlm.nih.gov/pubmed/29264472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2016-1053 |
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