ErbB Receptor-Driven Prolactinomas Respond to Targeted Lapatinib Treatment in Female Transgenic Mice

As ErbB receptors are expressed in prolactinomas and exhibit downstream effects on prolactin (PRL) production and cell proliferation, we generated transgenic mice using a PRL enhancer/promoter expression system to restrict lactotroph-specific expression of human epidermal growth factor receptor (EGF...

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Detaylı Bibliyografya
Yayımlandı:Endocrinology
Asıl Yazarlar: Liu, Xiaohai, Kano, Maya, Araki, Takako, Cooper, Odelia, Fukuoka, Hidenori, Tone, Yukiko, Tone, Masahide, Melmed, Shlomo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2015
Konular:
Cancer-Oncogenes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272404/
https://ncbi.nlm.nih.gov/pubmed/25375038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1627
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