ErbB Receptor-Driven Prolactinomas Respond to Targeted Lapatinib Treatment in Female Transgenic Mice

As ErbB receptors are expressed in prolactinomas and exhibit downstream effects on prolactin (PRL) production and cell proliferation, we generated transgenic mice using a PRL enhancer/promoter expression system to restrict lactotroph-specific expression of human epidermal growth factor receptor (EGF...

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Bibliografiset tiedot
Julkaisussa:Endocrinology
Päätekijät: Liu, Xiaohai, Kano, Maya, Araki, Takako, Cooper, Odelia, Fukuoka, Hidenori, Tone, Yukiko, Tone, Masahide, Melmed, Shlomo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Endocrine Society 2015
Aiheet:
Cancer-Oncogenes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272404/
https://ncbi.nlm.nih.gov/pubmed/25375038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1627
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