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HER2/ErbB2 Receptor Signaling in Rat and Human Prolactinoma Cells: Strategy for Targeted Prolactinoma Therapy

Dopamine agonist resistance or intolerance is encountered in approximately 20% of prolactinoma patients. Because human epidermal growth factor receptor 2 (HER2)/ErbB2 is overexpressed in prolactinomas and ErbB receptor ligands regulate prolactin (PRL) gene expression, we tested the role of HER2/ErbB...

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Autors principals: Fukuoka, Hidenori, Cooper, Odelia, Mizutani, Jun, Tong, Yunguang, Ren, Song-Guang, Bannykh, Serguei, Melmed, Shlomo
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089034/
https://ncbi.nlm.nih.gov/pubmed/21106881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0353
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