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Somatostatin receptor subtype 5 modifies hypothalamic-pituitary-adrenal axis stress function

Pituitary corticotroph somatostatin receptor subtype 5 (SSTR5) signals to inhibit adrenocorticotrophin (ACTH) secretion. As ACTH deficiency results in attenuated adrenal cortisol production and an impaired stress response, we sought to clarify the role of SSTR5 in modifying the hypothalamic/pituitar...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Yamamoto, Masaaki, Ben-Shlomo, Anat, Kameda, Hiraku, Fukuoka, Hidenori, Deng, Nan, Ding, Yan, Melmed, Shlomo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237446/
https://ncbi.nlm.nih.gov/pubmed/30282821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122932
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