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Somatostatin receptor subtype 5 modifies hypothalamic-pituitary-adrenal axis stress function

Pituitary corticotroph somatostatin receptor subtype 5 (SSTR5) signals to inhibit adrenocorticotrophin (ACTH) secretion. As ACTH deficiency results in attenuated adrenal cortisol production and an impaired stress response, we sought to clarify the role of SSTR5 in modifying the hypothalamic/pituitar...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Yamamoto, Masaaki, Ben-Shlomo, Anat, Kameda, Hiraku, Fukuoka, Hidenori, Deng, Nan, Ding, Yan, Melmed, Shlomo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237446/
https://ncbi.nlm.nih.gov/pubmed/30282821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122932
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