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Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice

Diet soda consumption has not been associated with tangible weight loss. Aspartame (ASP) commonly substitutes sugar and one of its breakdown products is phenylalanine (PHE), a known inhibitor of intestinal alkaline phosphatase (IAP), a gut enzyme shown to prevent metabolic syndrome in mice. We hypot...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Appl Physiol Nutr Metab
Main Authors: Gul, Sarah S., Hamilton, A. Rebecca L., Munoz, Alexander R., Phupitakphol, Tanit, Liu, Wei, Hyoju, Sanjiv K., Economopoulos, Konstantinos P., Morrison, Sara, Hu, Dong, Zhang, Weifeng, Gharedaghi, Mohammad Hadi, Huo, Haizhong, Hamarneh, Sulaiman R., Hodin, Richard A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686455/
https://ncbi.nlm.nih.gov/pubmed/27997218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/apnm-2016-0346
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