A Novel Approach to Maintain Gut Mucosal Integrity Using an Oral Enzyme Supplement

OBJECTIVE: To determine the role of intestinal alkaline phosphatase (IAP) in enteral starvation-induced gut barrier dysfunction and to study its therapeutic effect as a supplement to prevent gut-derived sepsis. BACKGROUND: Critically ill patients are at increased risk for systemic sepsis and, in som...

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Detalhes bibliográficos
Publicado no:Ann Surg
Main Authors: Hamarneh, Sulaiman R, Rafat Mohamed, Mussa M., Economopoulos, Konstantinos P., Morrison, Sara A., Phupitakphol, Tanit, Tantillo, Tyler J., Gul, Sarah S., Gharedaghi, Mohammad Hadi, Tao, Qingsong, Kaliannan, Kanakaraju, Narisawa, Sonoko, Millán, José L., van der Wilden, Gwendolyn M., Fagenholz, Peter J., Malo, Madhu S., Hodin, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034572/
https://ncbi.nlm.nih.gov/pubmed/25203888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000000916
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