Intestinal alkaline phosphatase promotes gut bacterial growth by reducing the concentration of luminal nucleotide triphosphates

The intestinal microbiota plays a pivotal role in maintaining human health and well-being. Previously, we have shown that mice deficient in the brush-border enzyme intestinal alkaline phosphatase (IAP) suffer from dysbiosis and that oral IAP supplementation normalizes the gut flora. Here we aimed to...

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Detalhes bibliográficos
Main Authors: Malo, Madhu S., Moaven, Omeed, Muhammad, Nur, Biswas, Brishti, Alam, Sayeda N., Economopoulos, Konstantinos P., Gul, Sarah Shireen, Hamarneh, Sulaiman R., Malo, Nondita S., Teshager, Abeba, Mohamed, Mussa M. Rafat, Tao, Qingsong, Narisawa, Sonoko, Millán, José Luis, Hohmann, Elizabeth L., Warren, H. Shaw, Robson, Simon C., Hodin, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Mucosal Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024727/
https://ncbi.nlm.nih.gov/pubmed/24722905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00357.2013
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