Eukaryotic-type serine/threonine kinase mediated phosphorylation at Thr(169) perturbs mycobacterial guanylate kinase activity

Guanylate kinase is an essential and conserved enzyme in nucleotide biosynthetic pathway that transfers phosphoryl group of ATP to GMP for yielding GDP. Here, we report the phosphorylation of guanylate kinase from Mycobacterium tuberculosis (mGmk) by eukaryotic-type Ser/Thr kinase, PknA. Mass spectr...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Biosci Rep
Hlavní autoři: S. Yadav, Ghanshyam, K. Ravala, Sandeep, Kachhap, Sangita, Thakur, Meghna, Roy, Abhishek, Singh, Balvinder, Karthikeyan, Subramanian, K. Chakraborti, Pradip
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686395/
https://ncbi.nlm.nih.gov/pubmed/28963370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20171048
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky