Eukaryotic-type serine/threonine kinase mediated phosphorylation at Thr(169) perturbs mycobacterial guanylate kinase activity

Guanylate kinase is an essential and conserved enzyme in nucleotide biosynthetic pathway that transfers phosphoryl group of ATP to GMP for yielding GDP. Here, we report the phosphorylation of guanylate kinase from Mycobacterium tuberculosis (mGmk) by eukaryotic-type Ser/Thr kinase, PknA. Mass spectr...

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Bibliografische gegevens
Gepubliceerd in:Biosci Rep
Hoofdauteurs: S. Yadav, Ghanshyam, K. Ravala, Sandeep, Kachhap, Sangita, Thakur, Meghna, Roy, Abhishek, Singh, Balvinder, Karthikeyan, Subramanian, K. Chakraborti, Pradip
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686395/
https://ncbi.nlm.nih.gov/pubmed/28963370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20171048
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