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Phosphorylation Modulates Catalytic Activity of Mycobacterial Sirtuins

Sirtuins are NAD(+)-dependent deacetylases involved in the regulation of diverse cellular processes and are conserved throughout phylogeny. Here we report about in vitro transphosphorylation of the only NAD(+)-dependent deacetylase (mDAC) present in the genome of Mycobacterium tuberculosis by eukary...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Yadav, Ghanshyam S., Ravala, Sandeep K., Malhotra, Neha, Chakraborti, Pradip K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860497/
https://ncbi.nlm.nih.gov/pubmed/27242704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00677
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