Yes-Associated Protein (YAP) Promotes Tumorigenesis in Melanoma Cells Through Stimulation of Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1)

YAP is a critical protein in cancer development and can induce transformative phenotypes in mammary epithelial cells. Previous studies have provided evidence that YAP can contribute to the metastatic behavior of melanoma, since specific knockdown of YAP leads to reduced metastatic and invasive capac...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Xiong, Huizi, Yu, Qian, Gong, Yu, Chen, Wenjuan, Tong, Yunlei, Wang, Yao, Xu, Hui, Shi, Yuling
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686191/
https://ncbi.nlm.nih.gov/pubmed/29138479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14764-4
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