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The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein
PrP(C) (cellular prion protein) is located at the surface of neuronal cells in detergent-insoluble lipid rafts, yet is internalized by clathrin-dependent endocytosis. As PrP(C) is glycosyl-phosphatidylinositol-anchored, it requires a transmembrane adaptor protein to connect it to the clathrin endocy...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783995/ https://ncbi.nlm.nih.gov/pubmed/17155929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061736 |
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