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The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein

PrP(C) (cellular prion protein) is located at the surface of neuronal cells in detergent-insoluble lipid rafts, yet is internalized by clathrin-dependent endocytosis. As PrP(C) is glycosyl-phosphatidylinositol-anchored, it requires a transmembrane adaptor protein to connect it to the clathrin endocy...

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Detalhes bibliográficos
Main Authors: Taylor, David R., Hooper, Nigel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783995/
https://ncbi.nlm.nih.gov/pubmed/17155929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061736
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