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The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein

PrP(C) (cellular prion protein) is located at the surface of neuronal cells in detergent-insoluble lipid rafts, yet is internalized by clathrin-dependent endocytosis. As PrP(C) is glycosyl-phosphatidylinositol-anchored, it requires a transmembrane adaptor protein to connect it to the clathrin endocy...

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Bibliografski detalji
Glavni autori: Taylor, David R., Hooper, Nigel M.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783995/
https://ncbi.nlm.nih.gov/pubmed/17155929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061736
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